Move at the speed of oncology with an integrated approach to development. Trust our team for efficient, cost-effective solutions that usher your therapy from early discovery all the way to the clinic.
Progress the early discovery phase of your research with help from a team that develops and executes more than 100 biochemical and cellular assays per year for an extensive range of target classes.
Select the best screening approach, design and optimize an effective campaign, and identify quality hits with help from our experienced team.
Expedite your hit ID, hit-to-lead and lead optimization for ADME and toxicology profiles with computer-aided (in silico) drug design.
Discover, analyze, engineer, and own exclusive therapeutic antibodies using the antibody discovery platform from our partner, Distributed Bio.
Make informed decisions from early discovery through your IND-enabling studies with data from our experienced drug discovery chemists.
Elucidate the physical properties of your compound and ensure you move your best candidate forward with help from our pharmaceutics experts.
Drive development at every stage with rich DMPK ADME data – define potency against targets and optimize PK, validate toxicology and predict DDIs.
Visualize and measure phenotypic changes at the subcellular level in disease relevant cell-based assays
Assess potency and selectivity, identify MoA vis COMPARE analysis, and analyze multi-drug resistance with PDX combination studies.
Find the most promising candidates, tumor histotypes and molecular subtypes for further testing by evaluating the potency of your compound against SOC drugs.
Power your drug screening, biomarker discovery and evaluation of disease pathophysiology with custom human stem cell assays.
Create complex custom knock-in and knock-out cell lines for target screening alone or alongside RNAi screening with our shRNA library.
Assess acute through chronic toxicity and carcinogenicity with our board-certified toxicologists, veterinary surgeons and pathologists, and regulatory specialists.
Assess how your therapeutic affects physiological function across key systems with our ICH core battery and supplementary safety tests.
Supplement your in-house capabilities or outsource your entire program to our extensive network of analytical laboratory facilities.
Characterize the ADME properties of your test articles throughout development with in vitro and in vivo drug metabolism and pharmacokinetic studies.
Evaluate your therapy’s exposure and binding to the target of interest and confirm expression of the desired pharmacology with early stage molecular imaging.
Gain insight to your therapy’s safety, efficacy, and MoA with anatomic and clinical pathology endpoints delivered by our expert veterinary pathologists.
Make confident research decisions from method development to clinical sample analysis with our accurate, reliable and efficient bioanalytical services.
Maximize your clinical budget with early phase biomarker data that drives your decision to progress further into trials.
Test your oncology antibodies, vaccines, cell and gene therapies and biosimilars in preparation for market with our robust GMP manufacturing services.